Paper on VASP-E in press at PLoS Computational Biology

Dr. Chen's new single author paper, "VASP-E: Specificity Annotation with a Volumetric Analysis of Electrostatic Isopotentials", is now in press at PLoS Computational Biology.  This paper describes a new algorithm for the volumetric comparison of electrostatic fields in protein-ligand binding cavities and protein-protein interfaces.  Dr. Chen demonstrated that this new kind of comparison could complement existing structure-based comparisons, and reveal amino acids that have an electrostatic influence on specificity.

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